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PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas

Diffuse large B-cell lymphomas in humans are associated with chromosomal rearrangements (∼40%) and/or mutations disrupting autoregulation (∼16%) involving the BCL6 gene. Studies of lymphoma development in humans and mouse models have indicated that lymphomagenesis evolves through the accumulation of...

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Detalhes bibliográficos
Main Authors: Baron, Beverly W., Anastasi, John, Hyjek, Elizabeth M., Bies, Juraj, Reddy, Poluru L., Dong, Jingfang, Joseph, Loren, Thirman, Michael J., Wroblewski, Kristen, Wolff, Linda, Baron, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326467/
https://ncbi.nlm.nih.gov/pubmed/22451912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201168109
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