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Involvement of the N-terminus of Kir6.2 in coupling to the sulphonylurea receptor
1. ATP-sensitive potassium (K(ATP)) channels are composed of pore-forming Kir6.2 and regulatory SUR subunits. ATP inhibits the channel by interacting with Kir6.2, while sulphonylureas block channel activity by interaction with a high-affinity site on SUR1 and a low-affinity site on Kir6.2. MgADP and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269423/ https://ncbi.nlm.nih.gov/pubmed/10381582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0325p.x |
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