Complementary regulation of anaesthetic activation of human (α(6)β(3)γ(2L)) and Drosophila (RDL) GABA receptors by a single amino acid residue

1. The influence of a transmembrane (TM2) amino acid located at a homologous position in human β(1) (S290) and β(3) (N289) GABA(A) receptor subunits and the RDL GABA receptor of Drosophila (M314) upon allosteric regulation by general anaesthetics has been investigated. 2. GABA-evoked currents mediat...

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Detalhes bibliográficos
Main Authors: Pistis, Marco, Belelli, Delia, McGurk, Karen, Peters, John A, Lambert, Jeremy J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269142/
https://ncbi.nlm.nih.gov/pubmed/9925873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.003ad.x
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