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Complementary regulation of anaesthetic activation of human (α(6)β(3)γ(2L)) and Drosophila (RDL) GABA receptors by a single amino acid residue
1. The influence of a transmembrane (TM2) amino acid located at a homologous position in human β(1) (S290) and β(3) (N289) GABA(A) receptor subunits and the RDL GABA receptor of Drosophila (M314) upon allosteric regulation by general anaesthetics has been investigated. 2. GABA-evoked currents mediat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269142/ https://ncbi.nlm.nih.gov/pubmed/9925873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.003ad.x |
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