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The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABA(A) receptor-mediated inhibition

Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a recently described ‘spillover’ mode of inhibi...

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Detalhes bibliográficos
Main Authors: Herd, Murray B, Lambert, Jeremy J, Belelli, Delia
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215602/
https://ncbi.nlm.nih.gov/pubmed/24773078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12601
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