Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones

During brain development the duration of miniature inhibitory postsynaptic currents (mIPSCs) mediated by GABA(A) receptors (GABA(A)Rs) progressively reduces, to accommodate the temporal demands required for precise network activity. Conventionally, this synaptic plasticity results from GABA(A)R subu...

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Veröffentlicht in:J Physiol
Hauptverfasser: Brown, Adam R, Herd, Murray B, Belelli, Delia, Lambert, Jeremy J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Neuroscience: Development/Plasticity/Repair
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293067/
https://ncbi.nlm.nih.gov/pubmed/25556800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.280263
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