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Inhibition of thalamic excitability by THIP: a selective role for δ-GABA(A) receptors

The sedative and hypnotic agent THIP is a GABA(A) receptor agonist that preferentially activates δ-subunit containing GABA(A) receptors (δ-GABA(A)Rs). To clarify the role of δ-GABA(A)Rs in mediating the sedative actions of THIP, we have utilised mice lacking the α1 or δ subunit in a combined electro...

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Detalhes bibliográficos
Main Authors: Herd, Murray B., Foister, Nicola, Chandra, Dev, Peden, Dianne R., Homanics, Gregg E., Brown, Verity J., Balfour, David J.K., Lambert, Jeremy J., Belelli, Delia
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788206/
https://ncbi.nlm.nih.gov/pubmed/19302153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.06680.x
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