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The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABA receptor
1. The γ-aminobutyric acid (GABA)-modulatory and GABA-mimetic actions of etomidate at mammalian GABA(A) receptors are favoured by β(2)- or β(3)- versus β(1)-subunit containing receptors, a selectivity which resides with a single transmembrane amino acid (β(2 N290), β(3 N289), β(1 S290)). Here, we ha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565349/ https://ncbi.nlm.nih.gov/pubmed/9630337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701787 |
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