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Insulin as an Autoantigen in NOD/Human Diabetes

Though multiple islet autoantigens are recognized by T lymphocytes and autoantibodies prior to the development of type 1A (immune mediated diabetes) there is increasing evidence that autoimmunity to insulin may be central to disease pathogenesis. Evidence is strongest for the NOD mouse model where b...

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Detalles Bibliográficos
Main Authors: Zhang, Li, Nakayama, Maki, Eisenbarth, George S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268871/
https://ncbi.nlm.nih.gov/pubmed/18178393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.11.005
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