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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

A fundamental question about the pathogenesis of spontaneous autoimmune diabetes is whether there are primary autoantigens. For type 1 diabetes it is clear that multiple islet molecules are the target of autoimmunity in man and animal models(1,2). It is not clear whether any of the target molecules...

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Dettagli Bibliografici
Autori principali: Nakayama, Maki, Abiru, Norio, Moriyama, Hiroaki, Babaya, Naru, Liu, Edwin, Miao, Dongmei, Yu, Liping, Wegmann, Dale R., Hutton, John C., Elliott, John F., Eisenbarth, George S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364531/
https://ncbi.nlm.nih.gov/pubmed/15889095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03523
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