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Insulin as an Autoantigen in NOD/Human Diabetes

Though multiple islet autoantigens are recognized by T lymphocytes and autoantibodies prior to the development of type 1A (immune mediated diabetes) there is increasing evidence that autoimmunity to insulin may be central to disease pathogenesis. Evidence is strongest for the NOD mouse model where b...

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Autors principals: Zhang, Li, Nakayama, Maki, Eisenbarth, George S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268871/
https://ncbi.nlm.nih.gov/pubmed/18178393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.11.005
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