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Insulin as a key autoantigen in the development of type 1 diabetes
Type 1 diabetes is a T-cell-mediated autoimmune disease against pancreatic beta cells. T cells target various antigens such as insulin, chromogranin A, glutamic acid decarboxylase and islet-specific glucose-6-phosphatase catalytic subunit-related protein. Elimination of insulin dramatically prevents...
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| Publicado no: | Diabetes Metab Res Rev |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5439426/ https://ncbi.nlm.nih.gov/pubmed/22069258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.1250 |
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