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Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members

BACKGROUND: Otopetrin 1 (Otop1) encodes a multi-transmembrane domain protein with no homology to known transporters, channels, exchangers, or receptors. Otop1 is necessary for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals and teleost fish that...

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Main Authors: Hughes, Inna, Binkley, Jonathan, Hurle, Belen, Green, Eric D, Sidow, Arend, Ornitz, David M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268672/
https://ncbi.nlm.nih.gov/pubmed/18254951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-41
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