Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members

BACKGROUND: Otopetrin 1 (Otop1) encodes a multi-transmembrane domain protein with no homology to known transporters, channels, exchangers, or receptors. Otop1 is necessary for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals and teleost fish that...

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Bibliografiske detaljer
Main Authors: Hughes, Inna, Binkley, Jonathan, Hurle, Belen, Green, Eric D, Sidow, Arend, Ornitz, David M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268672/
https://ncbi.nlm.nih.gov/pubmed/18254951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-41
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