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Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium

Otopetrin1 (Otop1) is a multitransmembrane domain protein required for the formation of otoconia in the vertebrate inner ear. Otoconia are complex calcium carbonate (CaCO(3)) biominerals that are required for the sensation of gravity. Examination of the phenotypes of animals with mutations or defici...

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Bibliografiske detaljer
Main Authors: Hughes, Inna, Saito, Mitsuyoshi, Schlesinger, Paul H., Ornitz, David M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924595/
https://ncbi.nlm.nih.gov/pubmed/17606897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705182104
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