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Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium

Otopetrin1 (Otop1) is a multitransmembrane domain protein required for the formation of otoconia in the vertebrate inner ear. Otoconia are complex calcium carbonate (CaCO(3)) biominerals that are required for the sensation of gravity. Examination of the phenotypes of animals with mutations or defici...

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Bibliographic Details
Main Authors: Hughes, Inna, Saito, Mitsuyoshi, Schlesinger, Paul H., Ornitz, David M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924595/
https://ncbi.nlm.nih.gov/pubmed/17606897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705182104
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