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Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells
Otopetrin 1 (Otop1) encodes a protein that is essential for development of otoconia. Otoconia are the extracellular calcium carbonate containing crystals that are important for vestibular mechanosensory transduction of linear motion and gravity. There are two mutant alleles of Otop1 in mice, titled...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046300/ https://ncbi.nlm.nih.gov/pubmed/21236346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.01.005 |
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