Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses

BACKGROUND: Mutations in the Otopetrin 1 gene (Otop1) in mice and fish produce an unusual bilateral vestibular pathology that involves the absence of otoconia without hearing impairment. The encoded protein, Otop1, is the only functionally characterized member of the Otopetrin Domain Protein (ODP) f...

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Detalhes bibliográficos
Main Authors: Hurle, Belen, Marques-Bonet, Tomas, Antonacci, Francesca, Hughes, Inna, Ryan, Joseph F, Eichler, Evan E, Ornitz, David M, Green, Eric D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038909/
https://ncbi.nlm.nih.gov/pubmed/21261979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-23
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