Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses

BACKGROUND: Mutations in the Otopetrin 1 gene (Otop1) in mice and fish produce an unusual bilateral vestibular pathology that involves the absence of otoconia without hearing impairment. The encoded protein, Otop1, is the only functionally characterized member of the Otopetrin Domain Protein (ODP) f...

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Autors principals: Hurle, Belen, Marques-Bonet, Tomas, Antonacci, Francesca, Hughes, Inna, Ryan, Joseph F, Eichler, Evan E, Ornitz, David M, Green, Eric D
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038909/
https://ncbi.nlm.nih.gov/pubmed/21261979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-23
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