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Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage

The initial comparison of the human and chimpanzee genome sequences revealed 16 genomic regions with an unusually high density of rapidly evolving genes. One such region is the whey acidic protein (WAP) four-disulfide core domain locus (or WFDC locus), which contains 14 WFDC genes organized in two s...

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Détails bibliographiques
Auteurs principaux: Hurle, Belen, Swanson, Willie, Green, Eric D.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800918/
https://ncbi.nlm.nih.gov/pubmed/17267810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6004607
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