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Ca(2+) oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca(2+) signal integrators

The role of Ca(2+) signaling in triggering hypertrophy was investigated in neonatal rat cardiomyocytes in vitro. We show that an increase in cell size and sarcomere reorganization were elicited by receptor agonists such as Angiotensin II, aldosterone, and norepinephrine and by a small rise in medium...

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Bibliografiske detaljer
Main Authors: Colella, Matilde, Grisan, Francesca, Robert, Valerie, Turner, Jay D., Thomas, Andrew P., Pozzan, Tullio
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268550/
https://ncbi.nlm.nih.gov/pubmed/18287024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712316105
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