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NFAT functions as a working memory of Ca(2+) signals in decoding Ca(2+) oscillation
Transcription by the nuclear factor of activated T cells (NFAT) is regulated by the frequency of Ca(2+) oscillation. However, why and how Ca(2+) oscillation regulates NFAT activity remain elusive. NFAT is dephosphorylated by Ca(2+)-dependent phosphatase calcineurin and translocates from the cytoplas...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169054/ https://ncbi.nlm.nih.gov/pubmed/12881417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg381 |
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