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Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds
Proteins that share common ancestry may differ in structure and function because of divergent evolution of their amino acid sequences. For a typical diverse protein superfamily, the properties of a few scattered members are known from experiment. A satisfying picture of functional and structural evo...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268138/ https://ncbi.nlm.nih.gov/pubmed/18227506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711589105 |
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