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N15 Cro and λ Cro: Orthologous DNA-binding domains with completely different but equally effective homodimer interfaces

Bacteriophage Cro proteins bind to target DNA as dimers but do not all dimerize with equal strength, and differ in fold in the region of the dimer interface. We report the structure of the Cro protein from Enterobacteria phage N15 at 1.05 Å resolution. The subunit fold contains five α-helices and is...

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Bibliografske podrobnosti
Main Authors: Dubrava, Matthew S., Ingram, Wendy M., Roberts, Sue A., Weichsel, Andrzej, Montfort, William R., Cordes, Matthew H.J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327278/
https://ncbi.nlm.nih.gov/pubmed/18369196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073330808
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