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Extreme divergence between one-to-one orthologs: the structure of N15 Cro bound to operator DNA and its relationship to the λ Cro complex

The gene cro promotes lytic growth of phages through binding of Cro protein dimers to regulatory DNA sites. Most Cro proteins are one-to-one orthologs, yet their sequence, structure and binding site sequences are quite divergent across lambdoid phages. We report the cocrystal structure of bacterioph...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hall, Branwen M, Roberts, Sue A, Cordes, Matthew H J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649833/
https://ncbi.nlm.nih.gov/pubmed/31180482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz507
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