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Evolutionary bridges to new protein folds: design of C-terminal Cro protein chameleon sequences

Regions of amino-acid sequence that are compatible with multiple folds may facilitate evolutionary transitions in protein structure. In a previous study, we described a heuristically designed chameleon sequence (SASF1, structurally ambivalent sequence fragment 1) that could adopt either of two natur...

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Detalhes bibliográficos
Main Authors: Anderson, William J., Van Dorn, Laura O., Ingram, Wendy M., Cordes, Matthew H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160206/
https://ncbi.nlm.nih.gov/pubmed/21676898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzr027
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