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Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn
The neonatal Fc receptor FcRn provides IgG molecules with their characteristically long half-lives in vivo by protecting them from intracellular catabolism and then returning them to the extracellular space. Other investigators have demonstrated that mice lacking FcRn are protected from induction of...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268137/ https://ncbi.nlm.nih.gov/pubmed/18272495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708960105 |
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