Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics

von Rath, Timo, Baker, Kristi, Dumont, Jennifer A., Peters, Robert T., Jiang, Haiyan, Qiao, Shuo-Wang, Lencer, Wayne I., Pierce, Glenn F., Blumberg, Richard S.
Veröffentlicht in Crit Rev Biotechnol (2013)

Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn

von Mezo, Adam R., McDonnell, Kevin A., Hehir, Cristina A. Tan, Low, Susan C., Palombella, Vito J., Stattel, James M., Kamphaus, George D., Fraley, Cara, Zhang, Yixia, Dumont, Jennifer A., Bitonti, Alan J.
Veröffentlicht 2008

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

von Powell, Jerry S., Josephson, Neil C., Quon, Doris, Ragni, Margaret V., Cheng, Gregory, Li, Ella, Jiang, Haiyan, Li, Lian, Dumont, Jennifer A., Goyal, Jaya, Zhang, Xin, Sommer, Jurg, McCue, Justin, Barbetti, Margaret, Luk, Alvin, Pierce, Glenn F.
Veröffentlicht 2012

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

von Dumont, Jennifer A., Liu, Tongyao, Low, Susan C., Zhang, Xin, Kamphaus, George, Sakorafas, Paul, Fraley, Cara, Drager, Douglas, Reidy, Thomas, McCue, Justin, Franck, Helen W. G., Merricks, Elizabeth P., Nichols, Timothy C., Bitonti, Alan J., Pierce, Glenn F., Jiang, Haiyan
Veröffentlicht 2012

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

von Bitonti, Alan J., Dumont, Jennifer A., Low, Susan C., Peters, Robert T., Kropp, Keith E., Palombella, Vito J., Stattel, James M., Lu, Yichun, Tan, Cristina A., Song, Jeffrey J., Garcia, Ana Maria, Simister, Neil E., Spiekermann, Gerburg M., Lencer, Wayne I., Blumberg, Richard S.
Veröffentlicht 2004

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients

von Shapiro, Amy D., Ragni, Margaret V., Valentino, Leonard A., Key, Nigel S., Josephson, Neil C., Powell, Jerry S., Cheng, Gregory, Thompson, Arthur R., Goyal, Jaya, Tubridy, Karen L., Peters, Robert T., Dumont, Jennifer A., Euwart, Donald, Li, Lian, Hallén, Bengt, Gozzi, Peter, Bitonti, Alan J., Jiang, Haiyan, Luk, Alvin, Pierce, Glenn F.
Veröffentlicht 2012

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A

von Mahlangu, Johnny, Powell, Jerry S., Ragni, Margaret V., Chowdary, Pratima, Josephson, Neil C., Pabinger, Ingrid, Hanabusa, Hideji, Gupta, Naresh, Kulkarni, Roshni, Fogarty, Patrick, Perry, David, Shapiro, Amy, Pasi, K. John, Apte, Shashikant, Nestorov, Ivan, Jiang, Haiyan, Li, Shuanglian, Neelakantan, Srividya, Cristiano, Lynda M., Goyal, Jaya, Sommer, Jurg M., Dumont, Jennifer A., Dodd, Nigel, Nugent, Karen, Vigliani, Gloria, Luk, Alvin, Brennan, Aoife, Pierce, Glenn F.
Veröffentlicht 2014