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Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics
Nearly 350 IgG-based therapeutics are approved for clinical use or are under development for many diseases lacking adequate treatment options. These include molecularly engineered biologicals comprising the IgG Fc-domain fused to various effector molecules (so-called Fc-fusion proteins) that confer...
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| Wydane w: | Crit Rev Biotechnol |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4876602/ https://ncbi.nlm.nih.gov/pubmed/24156398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07388551.2013.834293 |
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