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Investigation of the Influence of FcRn on the Distribution of IgG to the Brain
It has been suggested that the neonatal Fc receptor (FcRn) is a primary determinant of the distribution of IgG to the brain. In the present report, (125)I-labeled 7E3, a monoclonal IgG1 antibody, was injected intravenously to groups of FcRn-deficient mice and C57BL/6J control mice. Sub-groups of thr...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer US
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758122/ https://ncbi.nlm.nih.gov/pubmed/19636712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9129-9 |
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