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Structure of the 21–30 fragment of amyloid β-protein

Folding and self-assembly of the 42-residue amyloid β-protein (Aβ) are linked to Alzheimer's disease (AD). The 21–30 region of Aβ, Aβ(21–30), is resistant to proteolysis and is believed to nucleate the folding of full-length Aβ. The conformational space accessible to the Aβ(21–30) peptide is in...

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Detalhes bibliográficos
Main Authors: Baumketner, Andrij, Bernstein, Summer L., Wyttenbach, Thomas, Lazo, Noel D., Teplow, David B., Bowers, Michael T., Shea, Joan-Emma
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265091/
https://ncbi.nlm.nih.gov/pubmed/16731963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062076806
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