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Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule

Stress response pathways allow cells to sense and respond to environmental changes and adverse pathophysiological states. Pharmacological modulation of cellular stress pathways has implications in the treatment of human diseases, including neurodegenerative disorders, cardiovascular disease, and can...

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Detalhes bibliográficos
Main Authors: Trott, Amy, West, James D., Klaić, Lada, Westerheide, Sandy D., Silverman, Richard B., Morimoto, Richard I., Morano, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262981/
https://ncbi.nlm.nih.gov/pubmed/18199679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1004
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