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Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise

All cells have developed various mechanisms to respond and adapt to a variety of environmental challenges, including stresses that damage cellular proteins. One such response, the heat shock response (HSR), leads to the transcriptional activation of a family of molecular chaperone proteins that prom...

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Bibliographic Details
Main Authors: West, James D., Wang, Yanyu, Morano, Kevin A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472121/
https://ncbi.nlm.nih.gov/pubmed/22799889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300264x
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