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The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

Human APOBEC3G and several other APOBEC3 proteins have been shown to inhibit the replication of a variety of retrotransposons and retroviruses. All of these enzymes can deaminate cytosines within single-strand DNA, but the overall importance of this conserved activity in retroelement restriction has...

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Detalhes bibliográficos
Main Authors: Schumacher, April J., Haché, Guylaine, MacDuff, Donna A., Brown, William L., Harris, Reuben S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259018/
https://ncbi.nlm.nih.gov/pubmed/18184715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02391-07
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