Alpha/Beta Interferon Inhibits Cap-Dependent Translation of Viral but Not Cellular mRNA by a PKR-Independent Mechanism

The alpha/beta interferon (IFN-α/β) response is critical for host protection against disseminated replication of many viruses, primarily due to the transcriptional upregulation of genes encoding antiviral proteins. Previously, we determined that infection of mice with Sindbis virus (SB) could be con...

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Detalhes bibliográficos
Main Authors: Tesfay, Mulu Z., Yin, Jun, Gardner, Christina L., Khoretonenko, Mikhail V., Korneeva, Nadejda L., Rhoads, Robert E., Ryman, Kate D., Klimstra, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259014/
https://ncbi.nlm.nih.gov/pubmed/18160435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01784-07
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