Sindbis Virus Translation Is Inhibited by a PKR/RNase L-Independent Effector Induced by Alpha/Beta Interferon Priming of Dendritic Cells

The tropism of Sindbis virus (SB) for cells of the dendritic cell (DC) lineage and the virulence of SB in vivo are largely determined by the efficacy of alpha/beta interferon (IFN-α/β)-mediated antiviral responses. These responses are essentially intact in the absence of PKR and/or RNase L (K. D. Ry...

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Main Authors: Ryman, K. D., Meier, K. C., Nangle, E. M., Ragsdale, S. L., Korneeva, N. L., Rhoads, R. E., MacDonald, M. R., Klimstra, W. B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC544143/
https://ncbi.nlm.nih.gov/pubmed/15650175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1487-1499.2005
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