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Hepatitis C Virus Blocks Interferon Effector Function by Inducing PKR Phosphorylation

The mechanisms underlying hepatitis C virus (HCV) resistance to type 1 interferon (IFN) are not well understood. The recent development of a cell culture model of HCV infection allows analysis of host-virus interactions, including IFN resistance, in the context of the complete virus life cycle. In t...

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Détails bibliographiques
Auteurs principaux: Garaigorta, Urtzi, Chisari, Francis V.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905238/
https://ncbi.nlm.nih.gov/pubmed/20006840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.11.004
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