Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses

We examined the characteristics of interferon alpha/beta (IFN-α/β) induction after alphavirus or control Sendai virus (SeV) infection of murine fibroblasts (MEFs). As expected, SeV infection of wild-type (wt) MEFs resulted in strong dimerization of IRF3 and the production of high levels of IFN-α/β....

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Publicado no:Virology
Main Authors: Burke, Crystal W., Gardner, Christina L., Steffan, Joshua J., Ryman, Kate D., Klimstra, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381786/
https://ncbi.nlm.nih.gov/pubmed/19782381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.08.039
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