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Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice
North American eastern equine encephalitis virus (NA-EEEV) strains cause high mortality in humans, whereas South American strains (SA-EEEV) are typically avirulent. To clarify mechanisms of SA-EEEV attenuation, we compared mouse-attenuated BeAr436087 SA-EEEV, considered an EEEV vaccine candidate, wi...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404509/ https://ncbi.nlm.nih.gov/pubmed/19539968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.030 |
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