Identification of Cellular Proteins That Maintain Retroviral Epigenetic Silencing: Evidence for an Antiviral Response

Integrated retroviral DNA is subject to epigenetic gene silencing, resulting in loss of expression of viral genes as well as reporter or therapeutic genes transduced by retroviral vectors. Possible mediators of such silencing include the histone deacetylase (HDAC) family of cellular proteins. We pre...

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Bibliografiske detaljer
Main Authors: Poleshko, Andrey, Palagin, Ivan, Zhang, Rugang, Boimel, Pamela, Castagna, Carolyn, Adams, Peter D., Skalka, Anna Marie, Katz, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258957/
https://ncbi.nlm.nih.gov/pubmed/18094192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01882-07
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