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Identification of Cellular Proteins That Maintain Retroviral Epigenetic Silencing: Evidence for an Antiviral Response

Integrated retroviral DNA is subject to epigenetic gene silencing, resulting in loss of expression of viral genes as well as reporter or therapeutic genes transduced by retroviral vectors. Possible mediators of such silencing include the histone deacetylase (HDAC) family of cellular proteins. We pre...

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Main Authors: Poleshko, Andrey, Palagin, Ivan, Zhang, Rugang, Boimel, Pamela, Castagna, Carolyn, Adams, Peter D., Skalka, Anna Marie, Katz, Richard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258957/
https://ncbi.nlm.nih.gov/pubmed/18094192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01882-07
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