Identification of Cellular Proteins That Maintain Retroviral Epigenetic Silencing: Evidence for an Antiviral Response

Integrated retroviral DNA is subject to epigenetic gene silencing, resulting in loss of expression of viral genes as well as reporter or therapeutic genes transduced by retroviral vectors. Possible mediators of such silencing include the histone deacetylase (HDAC) family of cellular proteins. We pre...

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Hlavní autoři: Poleshko, Andrey, Palagin, Ivan, Zhang, Rugang, Boimel, Pamela, Castagna, Carolyn, Adams, Peter D., Skalka, Anna Marie, Katz, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258957/
https://ncbi.nlm.nih.gov/pubmed/18094192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01882-07
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