Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo

Tumor sequencing studies have emphasized the role of epigenetics and altered chromatin homeostasis in cancer. Mutations in DAXX, which encodes a chaperone for the histone 3.3 variant, occur in 25% of pancreatic neuroendocrine tumors (PanNETs). To advance our understanding of physiological functions...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wasylishen, Amanda R., Sun, Chang, Moyer, Sydney M., Qi, Yuan, Chau, Gilda P., Aryal, Neeraj K., McAllister, Florencia, Kim, Michael P., Barton, Michelle C., Estrella, Jeannelyn S., Su, Xiaoping, Lozano, Guillermina
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406367/
https://ncbi.nlm.nih.gov/pubmed/32821827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba8415
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