Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

Gastrointestinal (GI) syndrome is a serious side effect and dose-limiting toxicity observed in patients undergoing lower-abdominal radiotherapy. Previous mouse studies show that p53 gene dosage determines susceptibility to GI syndrome development. However, the translational relevance of p53 activity...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Pant, Vinod, Xiong, Shunbin, Wasylishen, Amanda R., Larsson, Connie A., Aryal, Neeraj K., Chau, Gilda, Tailor, Ramesh C., Lozano, Guillermina
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717251/
https://ncbi.nlm.nih.gov/pubmed/31409715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909550116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker