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p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo
Cell stress and DNA damage activate the tumor suppressor p53, triggering transcriptional activation of a myriad of target genes. The molecular, morphological, and physiological consequences of this activation remain poorly understood in vivo. We activated a p53 transcriptional program in mice by del...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519296/ https://ncbi.nlm.nih.gov/pubmed/32900967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008474117 |
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