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Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End

The p53 pathway is perturbed in the majority of human cancers. Although this most frequently occurs through the direct mutation or deletion of p53 itself, there are a number of other alterations that can attenuate the pathway and contribute to tumorigenesis. For example, amplification of important n...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Med
Glavni autori: Wasylishen, Amanda R., Lozano, Guillermina
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968169/
https://ncbi.nlm.nih.gov/pubmed/27329033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026211
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