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Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End
The p53 pathway is perturbed in the majority of human cancers. Although this most frequently occurs through the direct mutation or deletion of p53 itself, there are a number of other alterations that can attenuate the pathway and contribute to tumorigenesis. For example, amplification of important n...
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| Publicado no: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968169/ https://ncbi.nlm.nih.gov/pubmed/27329033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026211 |
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