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Human factors and pathways essential for mediating epigenetic gene silencing

Cellular identity in both normal and disease processes is determined by programmed epigenetic activation or silencing of specific gene subsets. Here, we have used human cells harboring epigenetically silent GFP-reporter genes to perform a genome-wide siRNA knockdown screen for the identification of...

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Main Authors: Poleshko, Andrey, Kossenkov, Andrew V, Shalginskikh, Natalia, Pecherskaya, Anna, Einarson, Margret B, Marie Skalka, Anna, Katz, Richard A
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169020/
https://ncbi.nlm.nih.gov/pubmed/25147916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.32088
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