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Human factors and pathways essential for mediating epigenetic gene silencing

Cellular identity in both normal and disease processes is determined by programmed epigenetic activation or silencing of specific gene subsets. Here, we have used human cells harboring epigenetically silent GFP-reporter genes to perform a genome-wide siRNA knockdown screen for the identification of...

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Detalhes bibliográficos
Main Authors: Poleshko, Andrey, Kossenkov, Andrew V, Shalginskikh, Natalia, Pecherskaya, Anna, Einarson, Margret B, Marie Skalka, Anna, Katz, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169020/
https://ncbi.nlm.nih.gov/pubmed/25147916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.32088
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