Human factors and pathways essential for mediating epigenetic gene silencing

Cellular identity in both normal and disease processes is determined by programmed epigenetic activation or silencing of specific gene subsets. Here, we have used human cells harboring epigenetically silent GFP-reporter genes to perform a genome-wide siRNA knockdown screen for the identification of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Poleshko, Andrey, Kossenkov, Andrew V, Shalginskikh, Natalia, Pecherskaya, Anna, Einarson, Margret B, Marie Skalka, Anna, Katz, Richard A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169020/
https://ncbi.nlm.nih.gov/pubmed/25147916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.32088
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge