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An Elaborate Pathway Required for Ras-Mediated Epigenetic Silencing
The conversion of a normal cell to a cancer cell is a stepwise process that typically involves the activation of oncogenes and inactivation of tumour suppressor and pro-apoptotic genes1. In many instances, inactivation of genes critical for cancer development occurs by epigenetic silencing that ofte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2147719/ https://ncbi.nlm.nih.gov/pubmed/17960246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06251 |
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