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An Elaborate Pathway Required for Ras-Mediated Epigenetic Silencing

The conversion of a normal cell to a cancer cell is a stepwise process that typically involves the activation of oncogenes and inactivation of tumour suppressor and pro-apoptotic genes1. In many instances, inactivation of genes critical for cancer development occurs by epigenetic silencing that ofte...

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Bibliografische gegevens
Hoofdauteurs: Gazin, Claude, Wajapeyee, Narendra, Gobeil, Stephane, Virbasius, Ching-Man, Green, Michael R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2147719/
https://ncbi.nlm.nih.gov/pubmed/17960246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06251
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