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Retroviral DNA Methylation and Epigenetic Repression Are Mediated by the Antiviral Host Protein Daxx
Integrated retroviral DNA is subject to epigenetic transcriptional silencing at different frequencies. This process is mediated by repressive DNA methylation and histone modifications on viral chromatin. However, the detailed mechanisms by which retroviral silencing is initiated and maintained are n...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3571491/ https://ncbi.nlm.nih.gov/pubmed/23221555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02026-12 |
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