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Antimycobacterial Activity and Mechanism of Action of NAS-91
The antimalarial agents NAS-91 and NAS-21 were found to express potent antimycobacterial activity, NAS-91 being more active than NAS-21. They partially inhibited mycolic acid biosynthesis and profoundly altered oleic acid production. The development of a cell-free assay for Δ9-desaturase activity al...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258518/ https://ncbi.nlm.nih.gov/pubmed/18086849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-07 |
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