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Antimycobacterial Activity and Mechanism of Action of NAS-91

The antimalarial agents NAS-91 and NAS-21 were found to express potent antimycobacterial activity, NAS-91 being more active than NAS-21. They partially inhibited mycolic acid biosynthesis and profoundly altered oleic acid production. The development of a cell-free assay for Δ9-desaturase activity al...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gratraud, Paul, Surolia, Namita, Besra, Gurdyal S., Surolia, Avadhesha, Kremer, Laurent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258518/
https://ncbi.nlm.nih.gov/pubmed/18086849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-07
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