Mass Spectrometry-Based Systems Approach for Identification of Inhibitors of Plasmodium falciparum Fatty Acid Synthase

The emergence of strains of Plasmodium falciparum resistant to the commonly used antimalarials warrants the development of new antimalarial agents. The discovery of type II fatty acid synthase (FAS) in Plasmodium distinct from the FAS in its human host (type I FAS) opened up new avenues for the deve...

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Hlavní autoři: Sharma, Shilpi, Sharma, Shailendra Kumar, Modak, Rahul, Karmodiya, Krishanpal, Surolia, Namita, Surolia, Avadhesha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913259/
https://ncbi.nlm.nih.gov/pubmed/17485508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00124-07
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