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Mass Spectrometry-Based Systems Approach for Identification of Inhibitors of Plasmodium falciparum Fatty Acid Synthase

The emergence of strains of Plasmodium falciparum resistant to the commonly used antimalarials warrants the development of new antimalarial agents. The discovery of type II fatty acid synthase (FAS) in Plasmodium distinct from the FAS in its human host (type I FAS) opened up new avenues for the deve...

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Détails bibliographiques
Auteurs principaux: Sharma, Shilpi, Sharma, Shailendra Kumar, Modak, Rahul, Karmodiya, Krishanpal, Surolia, Namita, Surolia, Avadhesha
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913259/
https://ncbi.nlm.nih.gov/pubmed/17485508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00124-07
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