EthA, a Common Activator of Thiocarbamide-Containing Drugs Acting on Different Mycobacterial Targets

Many of the current antimycobacterial agents require some form of cellular activation unmasking reactive groups, which in turn will bind to their specific targets. Therefore, understanding the mechanisms of activation of current antimycobacterials not only helps to decipher mechanisms of drug resist...

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Bibliographic Details
Main Authors: Dover, Lynn G., Alahari, Anuradha, Gratraud, Paul, Gomes, Jessica M., Bhowruth, Veemal, Reynolds, Robert C., Besra, Gurdyal S., Kremer, Laurent
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803108/
https://ncbi.nlm.nih.gov/pubmed/17220416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-06
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