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EthA, a Common Activator of Thiocarbamide-Containing Drugs Acting on Different Mycobacterial Targets

Many of the current antimycobacterial agents require some form of cellular activation unmasking reactive groups, which in turn will bind to their specific targets. Therefore, understanding the mechanisms of activation of current antimycobacterials not only helps to decipher mechanisms of drug resist...

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Detalhes bibliográficos
Main Authors: Dover, Lynn G., Alahari, Anuradha, Gratraud, Paul, Gomes, Jessica M., Bhowruth, Veemal, Reynolds, Robert C., Besra, Gurdyal S., Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803108/
https://ncbi.nlm.nih.gov/pubmed/17220416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-06
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